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Oprah Winfrey to Star in HBO Movie Immortal Life of Henrietta Lacks

Here’s something that might land atop Oprah’s Favorite Things List: a starring role in HBO’s next high-profile film.

The premium cable net announced Monday that Oprah Winfrey will star in The Immortal Life of Henrietta Lacks, based on Rebecca Skloot’s 2010 nonfiction bestseller.

The Immortal Life tells the true story of the titular African-American woman, whose cervical cancer cells were used to create the first immortal human cell line. Winfrey will portray Henrietta’s daughter, Deborah Lacks, as she searches to learn about the mother she never knew and comes to understand how the unauthorized harvesting of Henrietta’s cells in 1951 led to unprecedented medical breakthroughs.

Winfrey, who will also executive-produce The Immortal Life, has several acting projects lined up this year. She can next be seen recurring on the OWN drama Greenleaf (premiering June 21 at 10/9c) and will co-star in the network’s forthcoming series Queen Sugar, directed by Ava DuVernay.