Grey's Anatomy Exclusive: Neve Campbell Joins Season 9 Cast as Derek's Sister!

Get More: Casting News, Exclusive

Neve Campbell Grey's AnatomyAnother Shepherd sister is coming out of the woodwork on Grey’s Anatomy.

TVLine has learned exclusively that Party of Five vet Neve Campbell is set to appear in multiple episodes of ABC’s long-running medical drama as one of Derek’s (Patrick Dempsey) four sisters.

PHOTOS | Grey’s Anatomy First Look: Check Out the New Season 9 Cast Pics!

It’s not clear which sibling Campbell will play, but we can safely rule out Amelia (currently played by Caterina Scorsone on Private Practice) and Nancy (previously played by Embeth Davitz). That leaves Kathleen the psychiatrist or unnamed Sister No. 4.

The latest member of the Shepherd clan arrives during a particularly tumultuous time in Derek’s life. The severe hand injury he sustained in last May’s plane crash has brought his storied surgical career to a standstill. (Let’s hope there’s less carnage involved than when they played love interests in the horror flick Scream 3.)

RELATED | Grey’s Anatomy Boss Promises “Sexy” Reunion For [Spoiler]

Campbell, who can currently be seen in Encore’s 12-hour Titanic: Blood and Steel miniseries, is set to appear in at least two episodes of Grey’s.



Comments (78)

  • A little odd seeing as they were love interests in one of the Scream movies…

    Comment by nikki – October 10, 2012 02:16 PM PDT  Reply To This Post
    • Totally forgot about that!

      Comment by Lindz – October 10, 2012 02:19 PM PDT  Reply To This Post
    • I was thinking the same thing

      Comment by sally – October 10, 2012 04:14 PM PDT  Reply To This Post
    • LOL That’s hilarious; I totally forgot about that! :-)

      Comment by Sean Johnson – October 11, 2012 03:05 AM PDT  Reply To This Post
    • They weren’t love interests in Scream 3.

      Comment by Ethan – October 11, 2012 08:20 AM PDT  Reply To This Post
      • Totally right they were not love interest in scream 3. He was a police detective and she was the victim

        Comment by Jan – October 11, 2012 05:19 PM PDT  Reply To This Post
  • I like this! I missed Neve on my TV.

    Comment by Tracy – October 10, 2012 02:19 PM PDT  Reply To This Post
  • I definitely buy her and Amelia as sisters, appearance wise. I suppose Derek could be their brother.

    Comment by Robin – October 10, 2012 02:19 PM PDT  Reply To This Post
    • Me too, but I see more resemblance between Neve Campbell and Embeth Davitz

      Comment by Olivia – October 10, 2012 05:47 PM PDT  Reply To This Post
    • I was just thinking that they have consistently cast the Sheppard siblings really well. I have always thought the actress who plays Amelia looks like Patrick Dempsey’s family, and Neve Campbell further bridges the gap between their looks (and the other previously seen sister) pretty well.

      Comment by twilight123 – October 11, 2012 02:24 PM PDT  Reply To This Post
  • I’m kind of in love with this casting news!

    Comment by marge – October 10, 2012 02:22 PM PDT  Reply To This Post
  • TBH when I saw “Grey’s anatomy” and “sister” in the title I was hoping for Alex’s sister. Remember the 18 year old girl? If Alex’s mother and brother are sick/on pills and their father gone a long time ago, who take care of her? I’m hoping since season 6, it could be a great storyline for Alex even just for a couple of episodes.

    Comment by Azerty – October 10, 2012 02:24 PM PDT  Reply To This Post
    • I agree. I would rather watch a more interesting character like Alex have a sister or some other family member visit.

      Comment by Julie – October 10, 2012 02:29 PM PDT  Reply To This Post
    • would love to meet her. think lexi ainsworth would be great casting.

      Comment by Patti – October 10, 2012 03:26 PM PDT  Reply To This Post
  • Who the **** cares, we already got to meet two of his sisters! Another sister. Another “OMG my heand doesn’t work” (Burke, anyone?). They should stop repeating themselves, if not for killing/trying to kill anybody on each season, the show would be dead-end boring.

    Comment by Shannon – October 10, 2012 02:29 PM PDT  Reply To This Post
  • I wonder if this means all four sisters will be visiting at the same time.

    Comment by Tasha – October 10, 2012 02:33 PM PDT  Reply To This Post
    • OMG, I’d just *die* if Amelia and whoever Neve is playing were together at the same time. Amelia has to be one of the characters of my heart, and Neve Campbell of one of my first favorite actresses (though, today, she’s like normal, I’d be soooo happy!)

      Comment by Barbie Furtado – October 10, 2012 07:34 PM PDT  Reply To This Post
  • I think sibling-relationships are more interesting to explore than romantic ones, so i like this

    Comment by hello – October 10, 2012 02:34 PM PDT  Reply To This Post
    • Speaking of sibling relationships, I’m wondering when in the world Meredith will acknowledge her other half-sister Molly? All this stuff that has happened in her family with Thatcher, the death of his wife, his kidney transplant, and now Lexie’s death, and NO ONE mentions Molly AT ALL. All it takes is one line here and there to keep the continuity.

      Comment by Irishgirl – October 10, 2012 07:13 PM PDT  Reply To This Post
      • agreed! they make it like she never existed in the first place!

        Comment by Bonnie – October 10, 2012 10:05 PM PDT  Reply To This Post
      • You’re right, except it was a liver transplant.

        Comment by Basia – October 10, 2012 10:21 PM PDT  Reply To This Post
  • Great news! I’ve been in love with her since her days on #PartyofFive. She should have been a much bigger star than Jennifer Love Hewitt, in my opinion!

    Comment by whisperintherain – October 10, 2012 02:35 PM PDT  Reply To This Post
  • Doesn’t anyone think that this it is so very strange that Amelia, Nancy & Addison have NOT shown up in Seattle after hearing that Derek was in a plane crash? They’ll grieve over Mark from California but can’t find a flight to Seattle to visit with Derek? I find this to be just totally unbelieveable. Grey’s has Amelia & Addison as cross-over’s a couple of times & Nancy has been there – NOT ONE family member arrives in Seattle out of total concern over their brother who was in a plane crash & has lost the ability to perform surgery possibly forever? And not even so much as a phone call with the viewer seeing Amelia, Nancy & Addison talking with Derek to see how he & Meredith are. Hope this sister arrives to actually help her brother. I’m just totally blown away by this …..

    Comment by soxfan – October 10, 2012 02:40 PM PDT  Reply To This Post
    • callie’s folks and sis didn’t show up when she and her kid were almost goners and Arizona’s parents area AWOL even though she was lost in a plane crash and now lost her leg. Seems Grey’s can’t be bothered with parents?

      Comment by chris – October 10, 2012 02:59 PM PDT  Reply To This Post
      • Callie and Arizona’s parents were there for the wedding, at least.

        Meredith was the only one with family around :’( </3

        Comment by Barbie Furtado – October 10, 2012 07:30 PM PDT  Reply To This Post
      • Not true…they bother with parents/family when they need to kill them.

        Don’t be related to a doctor at Seattle Grace or you’re dead.

        Actually don’t be a doctor at Seattle Grace, because you’ll die

        In fact just don’t go to Seattle Grace.

        Comment by Josh – October 10, 2012 08:54 PM PDT  Reply To This Post
        • LOL – Seattle Grace is just a cover for another version of the “hell mouth” – with Mer as Buffy, Chris as Willow, etc etc

          Comment by chris – October 10, 2012 09:08 PM PDT  Reply To This Post
    • I think it’s weirder that no one has showed up for Amelia. She was in the hospital giving birth to a dead baby when Derek’s plane fell out of the sky!

      Comment by Viv – October 10, 2012 03:26 PM PDT  Reply To This Post
      • Amelia said that she did not want anyone in her family to know. Addison was going to call Derek but Jake stopped her. Unless Amelia told them, not sure why they would know.

        Comment by Ana – October 10, 2012 03:52 PM PDT  Reply To This Post
        • Amelia is not close to her family, it seems. From everything we can tell from PP, she’s never really been close to any of them, even though as Addison described it once, she’s had the best mother anyone could ever have had.

          Comment by Barbie Furtado – October 10, 2012 06:17 PM PDT  Reply To This Post
    • I agree when the death of dr mcdreamy passed on,not even his family showed up to be there granted I know this is tv but not very believable in my opinion

      Comment by Shaylene – October 10, 2012 06:04 PM PDT  Reply To This Post
  • Ugh – not in love with this … She’s okay but comes off very affected to me — is this the last season of Greys?

    Comment by Rachel – October 10, 2012 02:41 PM PDT  Reply To This Post
    • I believe Ellen and Patrick signed 2 year deals at the end of last season. Not sure about the others.

      Comment by Meg – October 10, 2012 03:02 PM PDT  Reply To This Post
  • So great and it does not bother me that they were love interest in Scream 3.

    Comment by sarah – October 10, 2012 02:42 PM PDT  Reply To This Post
  • So excited about this news!!! Really hope this means Derek will have a big, meaty storyline coming up this season and that his family sticks around for a while! Hoping this also means we will be seeing A LOT of MerDer! I would love to see Meredith and his family in a supporting role, with a storyline that is actually about Derek!

    Comment by Jen – October 10, 2012 02:44 PM PDT  Reply To This Post
    • Patrick asked to not have that much screen time to focus on racing, so I doubt it.

      Comment by Kate – October 10, 2012 04:58 PM PDT  Reply To This Post
  • Neve and Patrick weren’t lovers in Scream 3, while he was at her house at the end, it is never stated they were romantically involved. Fantastic news though! I love Neve!

    Comment by Jason – October 10, 2012 02:54 PM PDT  Reply To This Post
    • Clearly you are skimming the article & comments as it is written love/romantic interests, which they were, as evident of (especially) the last scene of scream 3. If you are going to comment on other articles & peoples posts, at least read through them before doing so.

      Comment by piper – October 10, 2012 04:22 PM PDT  Reply To This Post
      • I’m sorry but the last scene doesn’t prove anything. All he does is ask her to come in to watch the movie. The love interest is what you have interpreted. For the record, I was not skimming through the article. I read it in its entirety.

        Comment by Jason – October 10, 2012 08:33 PM PDT  Reply To This Post
        • Come on, you’d have to be blind and deaf not to see that a burgeoning romantic relationship between Sidney Prescott and Detective Mark Kincaid was strongly suggested at the end of Scream 3. Seriously, it was blatant.

          Comment by whisperintherain – October 11, 2012 04:07 AM PDT  Reply To This Post
  • Great news, She’s the perfect match for this role! I thinking She’s beautiful, a great actress and you’d believe Derek and Amelia and her to be siblings. Looking forward to seeing her on the show!

    Comment by Caro – October 10, 2012 02:57 PM PDT  Reply To This Post
  • Love interests don’t last long in Scream movies.

    Comment by BrianR – October 10, 2012 02:58 PM PDT  Reply To This Post
  • I wonder if she is the tall dark new female version of mark that is suppose to show up and help arizona get her life back?

    Comment by chris – October 10, 2012 03:01 PM PDT  Reply To This Post
  • This one better have kids. I guess they forgot that Derek mentioned he had 9 nieces and 6 nephews in season 1.

    Comment by Mohammad – October 10, 2012 03:04 PM PDT  Reply To This Post
    • I think his other sister, Nancy, has kids. Did they not mention that at all when she was on? Either way, yeah, one of his sisters much have a bunch of kids.

      Comment by Mikaylah – October 10, 2012 03:11 PM PDT  Reply To This Post
    • 9 NIECES AND 5 NEPHEWS

      Comment by jamie – October 10, 2012 09:57 PM PDT  Reply To This Post
      • Since Amelia doesn’t have any kids I guess it means that the other three sisters have 14 between them. I’m glad at least someone in his family is showing up.

        Comment by Sara – October 11, 2012 12:48 PM PDT  Reply To This Post
  • I like this bit of casting, and I’m exciting to meet another one of Derek’s sisters. I absolutely adore Amelia on PP.

    Comment by Mikaylah – October 10, 2012 03:12 PM PDT  Reply To This Post
  • This is cool. She’s a pretty big name so it’ll be good for the show. Plus, it’s about time that a family member shows up to check up on one of our doctors. It’s unrealistic for them to go through this much without so much as a mention of their families. Hope we get a visit from Arizona’s parents as well. She’s the survivor with the most damage and I can’t believe that her parents are MIA. At least her mom should come around. Hear Shonda?

    Comment by Ana – October 10, 2012 03:28 PM PDT  Reply To This Post
  • I’m happy to see more of Derek’s sisters. Glad this is happening. Just don’t kill her, ok?

    Comment by Ana – October 10, 2012 03:53 PM PDT  Reply To This Post
  • It’s a television show, it cannot fit all aspect of ‘reality’ into one hour (minus commercial time, it’s actually 42mins); so, to all the people complaining about the lack of family members filling up the the first two episodes of this season, please stop whining. Think about it: If all the siblings and parents were present, it would take away from the meat of the show and the original characters. There is such a large cast with complex storylines that Shonda needs every last second in those 42mins to try to weave her tales. If she introduced the families, you’d all be whining that there wasn’t enough ‘MerDer’ or ‘Calzona’ time. T.V., it’s fictional, it’s entertainment ~ what you don’t see during the 42 minutes, use your imagination! Picture the family members calling while your favourite characters are off-screen, Skyping with their parents and siblings; heck, even imagine a stressed-out Callie picking up Arizona’s parents at the airport in an attempt to break her depression by having the Colonel get her to ‘snap out of it’ ~ just because you didn’t ‘see’ it, doesn’t mean it didn’t happen! Change of topic: Yeah, Neve! Love her and cannot wait to see her on my favourite show :)

    Comment by Jo – October 10, 2012 04:09 PM PDT  Reply To This Post
    • Agreed. Also, the first episode was 30 days after the end of the second episode, so who knows who visited in that time.

      Comment by kjess – October 10, 2012 04:25 PM PDT  Reply To This Post
    • Well said

      Comment by Trish – October 10, 2012 05:36 PM PDT  Reply To This Post
    • This is by far the most intelligent comment I have read on a very long time! Thank you for pointing out the supposedly obvious!

      Comment by Bhollu – October 11, 2012 05:32 PM PDT  Reply To This Post
  • FML. I’ve been *so* strong quitting Grey’s Anatomy. Now this??? :( If she’s the psychiatrist???? I won’t be able to resist!!! GAH!!! She should’ve gone to PP to visit Lil Sis Amy instead! :/ Neve Cambpell was my first girl crush as at nine years old I wanted to be Sydney Prescott. I thought she kicked ass! <3

    Comment by Barbie Furtado – October 10, 2012 04:15 PM PDT  Reply To This Post
    • PP isn’t going to attract any “name” actor in it’s final season. They should have called TOD last season.

      Comment by Lindy – October 11, 2012 05:37 PM PDT  Reply To This Post
  • Why always happens horrible things im Seatle?? I would be afraid in that hospital, especially if I were a doctor. I dont like everyone dye George, Lexie, Sloan… And the calli’s girlfriend lost her leg.. WTF! its so awfull!!!!

    Comment by Angels – October 10, 2012 05:05 PM PDT  Reply To This Post
  • She probably will be the psychiatrist as everyone is all mentally instable after the plane crash.

    Comment by JDTC@aol.com – October 10, 2012 05:19 PM PDT  Reply To This Post
    • Could make for an interesting arc.. If she goes around counseling each of our core cast kind of like Diann Carrol did as Burke’s mom.. She set a bunch of people straight when she visited.. And it could get us back to a semi happy drama.. At least for a better part of the season.. Then get back to the heavy stuff.. I mean it is a TV drama, after all.. Would be dull if we didn’t have a great disaster every other season. But I’m ready for some happier times.. :)

      Comment by DarkDefender – October 10, 2012 05:58 PM PDT  Reply To This Post
  • Welcome home my sweet Julia Salinger from Party of Five… Neve must have her own TV Show. I’m the only one who beg for a Party of Five TV Reunion?

    Comment by Fernanda – October 10, 2012 07:07 PM PDT  Reply To This Post
  • I love her in the “Scream” films and I love “Grey’s Anatomy”, so this should be gold!

    Comment by DL – October 10, 2012 08:20 PM PDT  Reply To This Post
  • Weird that pretty much everyone on Greys worked with one another before.. Like Valentine for example, That had Katherine Heigl, and Jessica Capshaw. Then later Jessica Capshaw worked with Chyler Leigh in The Practice.. Patrick Dempsey probably has worked with a few others in something too.. Theres like 6 degrees of Greys everywhere.. oooh Scott Foley was another.. he was in scream..

    Comment by edizzle – October 10, 2012 08:32 PM PDT  Reply To This Post
  • Love this! Will be weird to see them together and brother as sister but I’ve been clamming for a Shepherd Family reunion. I guess having another sister come on would be great. If Derek’s hand was going to be a problem then I would say that its Kathleen the psychiatrist. Maybe she’s come on behalf of their mother to help Derek. Should be interesting to see how she gets on with Mer and Zola.

    Comment by shuayb – October 10, 2012 09:09 PM PDT  Reply To This Post
  • IT SHOULD BE A SHEPHERD FAMILY REUNION MOTHER, 4 SISTERS , DEREK BEACUSE NO HAND FOR A WHILE AND HE LOST HIS ( BROTHER) SR SAID THAT WOULD HAPPEN LAST SEASON IT NEVER DID HAPPEN!!!

    Comment by jamie – October 10, 2012 09:54 PM PDT  Reply To This Post
  • I’ll bet she’s going to be Kathleen the shrink who’ll help Derek with the problems with his hand and not being able to operate. It would be nice if Tyne Daley stopped by too.

    Comment by Dawn – October 11, 2012 03:33 AM PDT  Reply To This Post
  • so I wonder if this will be the love intrest they were teasing us with for Alex

    Comment by heather – October 11, 2012 05:54 AM PDT  Reply To This Post
    • Alex’s love interest is someone who will be sticking around long term. Neve is only going to guest star for a couple of episodes so she’s surely not the love interest.

      Comment by Julie – October 11, 2012 06:54 AM PDT  Reply To This Post
  • Remember when she guest starred on Medium yet about 4 or 5 of her PO5 co-stars guested on Ghost Whisperer? Fun times.

    Comment by Keenan – October 11, 2012 06:04 AM PDT  Reply To This Post
  • Agree. I am a true fan. But it’s very repetitive. Writers are fond of tragedy not drama. Btw bring Essie back…. tgat never had closure. Now that’s drama worth watching!!!!

    Comment by Dee – October 11, 2012 07:08 AM PDT  Reply To This Post
  • Patrick Dempsey was in Maid of Honor with Kevin McKidd who plays Owen on Greys….before Owen came to Greys. Actually Scott Foley ans Patrick Dempsey and Neve Campbell were all in the same Scream movie. Neve and Patrick were in fact love interests for whoever it was that said they weren’t.

    Comment by Sam – October 11, 2012 08:31 AM PDT  Reply To This Post
    • watch the movie again they were not involved in a romantic way.

      Comment by Jan – October 11, 2012 05:25 PM PDT  Reply To This Post
  • You also have to remember the families could have shown up after the crash we started the season a month after…we didn’t even get a reaction for Lexie yet….I think they still have more story to tell. You don’t know that their families didn’t show up after the plane crash.

    Comment by Sam – October 11, 2012 09:21 AM PDT  Reply To This Post
  • Talk about misleading:
    1. Neve Campbell Joins Season 9 Cast (sounds like new cast memeber) HEADLINE
    2. “Set to appear in MULTIPLE episodes” first paragraph
    3. Campbell …. is set to appear in at least TWO episodes of Grey’s. (last sentence)

    Comment by Chicago Dan – October 11, 2012 09:37 AM PDT  Reply To This Post
  • why all the siblings and the momy are going to Derek’s rescue everytime he has a cough ? he has a support systeme of friends and a wife and a daughter? Amelia is alone in L-A battling addiction and none of the sisters and worse her mom are there for her? nobody? it doesn’t make any sense!

    Comment by Ex FromTheLeft (@ExFromTheLeft) – October 14, 2012 07:06 AM PDT  Reply To This Post
  • TBH I would love for Izzie to come back, in tow with a little kid. Grey’s never has wrapped up the frozen sperm and egg from when she had cancer. It would be kool to see her come back, surprise! I named him Alex after his daddy….

    Comment by Vannessa – November 5, 2012 04:12 PM PDT  Reply To This Post
  • This is the right blog for anyone who really wants to find out about this topic. You understand a whole lot its almost hard to argue with you (not that I really would want to…HaHa). You definitely put a brand new spin on a topic which has been written about for ages. Great stuff, just great!

    Comment by Johnson's Baby Relief Kit – November 9, 2012 03:55 AM PDT  Reply To This Post

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