How Grey's Anatomy Has Handled Many High-Profile Exits Over the Years

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While Grey’s Anatomy fans continue wonder — and worry about — how original cast member Justin Chambers will be written off, especially since his last episode as Alex Karev has already aired, TVLine has decided to review not only how the ABC drama handled 15 other high-profile exits but READ MORE & VIEW PHOTOS

Stars Who Almost Played Other TV Roles — on Grey's Anatomy, NCIS, Lost, Gilmore Girls, Friends and Other Shows

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Actors Almost Cast on TV Shows

Somewhere, there’s an alternate universe where Rob Lowe practiced medicine not on Code Black, but as Grey’s Anatomy‘s McDreamy. Where Katie Holmes played Orange Is the New Black‘s Piper Chapman. And where Game of Thrones‘ Iwan Rheon almost played Game of Thrones‘… Jon Snow?! READ MORE & VIEW PHOTOS

Which 'Crisis' Absence Was Most Odd? Who Is Grey's New Person? Did NCIS Waste Bobby Ewing? And More TV Qs!

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Crisis on Infinite Earths

We’ve got questions, and you’ve (maybe) got answers! With another week of TV gone by, we’re lobbing queries left and right about shows including Grey’s Anatomy, Manifest, the Arrowverse and NCIS! READ MORE

Grey's Anatomy: 5 Dream 'Farewell, Alex Karev' Story Arcs We'd Have Liked to Have Seen — Plus, 5 Really Dark Ones

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High on the list of things that we Grey’s Anatomy fans dislike about the abrupt departure of original cast member Justin Chambers is the fact that he’s already gone — meaning we didn’t even get a chance to “say goodbye,” as it were, to his beloved character READ MORE & VIEW PHOTOS