Mad Men's Most Memorable Guest Stars

Marshall Allman (True Blood) as Miss Farrell's brother

Adam Kaufman (Dawson's Creek) as door-to-door air conditioning salesman Bob Shaw, about whom Betty has sexual fantasies

Alexis Bledel (Gilmore Girls) as Beth Dawes, who briefly has an affair with Pete

Anna Camp (True Blood, The Good Wife) as Bethany Van Nuys, a blind date set up for Don by Jane and Roger

Anne Dudek (House) as Betty's neighbor, Francine Hanson

Bess Armstrong (My So-Called Life) as a psychiatrist who doses Roger and Jane with LSD

Caity Lotz (Arrow) as Don's "niece," Stephanie Horton

Charles Shaughnessy (The Nanny) as Saint John Powell, the managing director of London-based advertising firm Puttnam, Powell & Lowe

Colin Hanks (Fargo, Roswell) as Father John Gill

Danielle Panabaker (The Flash) as a flight attendant who had sex with Roger

Danny Strong (Gilmore Girls, Buffy the Vampire Slayer) as Danny Siegel, a copywriter for Sterling Cooper Draper Pryce

Darby Stanchfield (Scandal) as Glen's mother Helen Bishop

David James Elliott (JAG) as Dave Wooster, another ad man who courts Don

Dennis Haskins (Saved By the Bell) as a Cool Whip test-kitchen scientist

Devon Gummersall (My So-Called Life) as Peggy's date Stevie

Elizabeth Reaser (Grey's Anatomy) as Diana, a waitress with whom Don becomes fixated

Gabriel Mann (Revenge) as Arthur Case, who pursued Betty at the stables

James Wolk (Political Animals, Happy Endings) as Bob Benson, Sterling Draper Cooper Pryce's most mysterious employee — and wearer of short shorts

Jessy Schram (Falling Skies, Veronica Mars) as Bonnie Whiteside, Pete's real estate girlfriend in LA

Joe O'Connor (Clarissa Explains It All) as Trudy's father Tom Vogel

Julie McNiven (Supernatural) as Hildy, Pete's secretary at Sterling Cooper

Kristen Schaal (The Last Man on Earth) as a switchboard operator who briefly appears in the pilot

Kristoffer Polaha (Life Unexpected) as Carlton Hanson, the husband of Betty's friend Francine (played by Anne Dudek)

Larisa Oleynik (The Secret World of Alex Mack) as Ken's wife Cynthia

Laura Ramsey (Hindsight) as Don's LA fling, fittingly named Joy

Mädchen Amick (Witches of East End, Gilmore Girls) as Don's ex-lover Andrea Rhodes

Madison McLaughlin (Supernatural) as Sarah, a fast friend of Sally's who tries to hit on Don

Marguerite Moreau (Grey's Anatomy, Life as We Know It) as a call girl who had a dalliance with Roger

Matt Long (Jack & Bobby) as Joey Baird, a freelance artist at Sterling Cooper Draper Pryce

Naturi Naughton (The Playboy Club) as Toni Charles, a Playboy Bunny and Lane Pryce's girlfriend

Neve Campbell (Party of Five) as a fellow passenger on Don's red-eye flight

Nora Zehetner (Everwood) as Don's nurse neighbor Phoebe

Parker Young (Enlisted, Suburgatory) as Jim Hanson, a handsome guy in Pete's Drivers Ed class

Patrick Fischler (Lost) as shock-comic Jimmy Barrett

Paul Johansson (One Tree Hill) as McCann Erickson exec Ferguson Donnelly

Ryan Cartwright (Bones) as Lane Pryce's secretary John Hooker

Ryan McPartlin (Chuck) as Betty's one-night stand

Sammi Hanratty (Pushing Daisies) as Sally's boarding school friend Millicient

Sam Page (Greek, Gossip Girl) as Joan's ex-husband Greg

Sarah Drew (Grey's Anatomy, Everwood) as Sal's wife Kitty

Ted McGinley (Married With Children) as Mel, the head writer on Megan Draper's soap opera

William Mapother (Lost) as Randall Walsh, Roger's crazy insurance magnate buddy

Zosia Mamet (Girls) as Joyce Ramsay, an assistant photo editor at Life magazine and Peggy's friend