What to Watch Thursday: Big Bang, Grey's and 5 Other Premieres, the Louie Finale and More

On TV this Thursday: Another big night of premieres, TVLiners, so I hope you’ve been pacing yourselves. Grey’s Anatomy, The Big Bang Theory, Two and a Half Men, Person of Interest and Scandal all return for a new season. Plus, ABC takes a deep dive on a Last Resort and CBS’ new take on Sherlock is Elementary. As a supplement to TVLine’s original features (always linked within) here are 10 programs to watch for tonight.

8 pm Last Resort (ABC) | Series premiere: Shawn Ryan (The Shield) and Karl Gajdusek bring us the crew of a U.S. Naval submarine, commanded by Andre Braugher (Homicide), that finds itself under attack – by its own country — after questioning orders to fire at Pakistan. The cast also includes Scott Speedman (Felicity), Robert Patrick (The Unit), Autumn Reeser (No Ordinary Family), Daisy Betts (Persons Unknown) and Dichen Lachman (Dollhouse). TVLine raised its periscope to check out the new drama; see what we thought.

8 pm The Vampire Diaries (The CW) | Repeat to Revisit: Something kinda huge happens to Elena in this episode aka the Season 3 finale. If you haven’t seen it yet but plan to watch Season 4 – which debuts Oct. 11 – you might wanna do so pronto.

8 pm The Big Bang Theory (CBS) | Season 6 premiere: Wolowitz tries to broker peace between his mom and Bernadette – from space, mind you – while Raj is a lonely singleton among his paired-off friends. TVLine caught up with some of the cast at the Emmys; click here to hear them preview what’s ahead.

8:30 pm Two and a Half Men (CBS) | Season 10 premiere: Michael Bolton (who, I have to say, won me over a little by taking part in this Lonely Island bit) plays himself as Walden plans a romantic birthday celebration for Zoey. The king of adult contemporary “kind of becomes a friend of Walden’s in a way,” executive producer Jim Patterson says. “And he’s just really funny.”

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9 pm Person of Interest (CBS) | Season 2 premiere: Reese needs the help of Detectives Carter and Fusco – and gets an assist from a uniquely talented, ferocious new ally — to get a kidnapped Finch back from his hacker nemesis, Root. Read scoop on the new season here, and hit comments to get in your final guesses on how the Machine supplies each week’s number.

9 pm Grey’s Anatomy (ABC) | Season 9 premiere: In the not-quite-immediate wake of the plane crash that killed (at least) Lexie, the Seattle Grace docs try to deal with loss and change. (Hang on, Grey’s fans. Less-dark, less-twisty and sexier stuff is on the horizon.)

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10 pm Elementary (CBS) | Series premiere: This modern-day riff on Sherlock Holmes presents him as a former Scotland Yard detective and recovering addict (played by Eli Stone’s Jonny Lee Miller) whose sober companion, Watson (Southland’s Lucy Liu), doubles as his sidekick. How does it hold up to other recent Holmes rehashings? Read our review.

10 pm Scandal (ABC) | Season 2 premiere: Olivia gave up her White House (ahem) “access” at the end of last season, but is still helping D.C. power players who get caught in PR nightmares. But first, the revelation of Quinn’s real identity forces Pope & Associates to swing into action, while Cyrus and Mellie each put President Grant in a compromising position. (Read TVLine’s in-depth preview.)

10 pm Louie (FX) | Season 3 finale: Louie struggles through the holidays… and he’ll have even more struggles ahead when the series returns next season.

Which of the above is must-see for you? Also, hit Comments to offer your own tune-in suggestions.