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House's Hugh Laurie Opens Up About Olivia Wilde's Exit: 'There Is Great Sadness'

House will be minus Thirteen after next Monday’s episode as Olivia Wilde goes off to fulfill her movie star destiny. And while the show’s titular grump will no doubt dull his grief with Vicodin, Hugh Laurie openly admits the actress will be sorely missed. READ MORE & WATCH VIDEO

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Exclusive: House Boss on Losing Lisa (and Olivia), Getting Back to the Show's Core Values, and a Possible Series-Ending Huddy Reunion

As House makes what could be its final rounds on television, series creator David Shore is determined to get the heart of the show beating again. That means putting the focus back on the weekly medical cases and, more importantly, Dr. Crankypants himself. But first, there’s fallout from events both onscreen (carmageddon) and off (farewell, Lisa Edelstein) that must be dealt with. In the following Q&A, Shore reveals why he’s sending House directly to jail, previews the new blood coming to Princeton-Plainsboro, and answers the question that’s been bugging me since May: Will Cuddy check back in before House checks out for good. READ MORE