Alyson HanniganThough she just signed on as host of Penn & Teller: Fool Us, Buffy’s erstwhile Willow and her new colleagues should be able to work the magic necessary for her to do two series at once.
Felicia DayNot only does the casualty of Dr. Horrible’s Sing-Along Blog have the chops to hold her own among Grey’s heavyweights, she also has a voice that practically demands another musical episode.
Mallory JansenSince it appears that ABC is pulling the plug on Galavant, maybe the network will d’dew us a favor and let Madalena’s enchanting portrayer be the one to bring Megan back to life.
Sarah BrownOn soap after soap, the Daytime Emmy winner proved that she could throw sparks with just about anybody. So she’d have no trouble turning up the heat with Megan’s old flame, Nathan.
Rachel NicholsFresh off her Chicago Fire run (where she “burned” poor Severide a bit), the Continuum/Alias alum seems overdue to heat things up in Shondaland.
Lauren AmbroseHot off her stint as The X-Files’ Einstein, the Six Feet Under alum would be believable both as a passionate doctor and someone whose loss could make enemies of the men who loved her.
Alicia WittConsidering the impression that she made in a single episode of The Walking Dead, Grey’s would have to be as brain-dead as a zombie not to want her scrubbing in at Grey Sloan.
Rachelle Lefevre If Kevin McKidd had a female counterpart, wouldn’t she be the spitting image of Under the Dome’s leading lady? She’s strong, striking and a redhead to boot.