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Grey's Anatomy First Look Video: What Is Meredith and Derek's Next Crisis?

It’s not easy being Drs. Meredith Grey and Derek Shepherd, especially during this eighth season of ABC’s Grey’s Anatomy.

Grey’s Anatomy Mystery: Where the Heck Is Lexie?

Already their only recently official marriage has been fractured by Mer’s tampering with the Alzheimer’s trial, followed by her ill-advised decision to disappear with Zola when the social worker caught wind of the prospective parents’ assorted setbacks. Indeed, no sooner had they laid hands on the dream of taking the tot into their care than she was plucked away, fate unknown.

Well, as seen in the new promo for this season’s fifth episode,”Love, Loss and Legacy,” Zola is back — and not in a way that will put a smile on Mer and Der’s faces.

Casting News: Debbie Allen Goes Grey’s as Jackson’s Mom

Press PLAY below to watch the promo for next week’s “history-making, love-making, Jackson-spanking*, pulse-pounding, life-changing” hour.

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* These actual words did not make it into the promo but were in TVLine’s Thursday “What to Watch” list, and even I’m a bit spooked by my predictive skills.